cyclophosphamide will raise the stage or impact of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unidentified.
Be mindful at this dose, Except you’ve built up some tolerance towards the smart drug. Break up dosing advised each day. Not just encouraged for any person but long run customers.
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indinavir will boost the level or outcome of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
modafinil boosts levels of eluxadoline by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Observe. Like a precautionary measure as a consequence of incomplete information on the metabolism of eluxadoline, use warning when coadministered with potent CYP2C19 inhibitors.
The advisable dosage of PROVIGIL for clients with SWD is 200 mg taken orally after every day as an individual dose around 1 hour prior to the beginning in their get the job done change.
Virtually all medicines that enter your body are metabolized by the liver. The liver uses a list of enzymes to stop working chemical compounds. Each one is coded by a selected gene, which we check with since the CYP450 isoenzymes.
PROVIGIL is contraindicated in clients with regarded hypersensitivity to modafinil or armodafinil or its inactive elements [see WARNINGS AND PRECAUTIONS].
apalutamide will reduce the level or impact of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of read more or Use Alternate Drug. Coadministration of apalutamide, a strong CYP3A4 inducer, with medicine which are CYP3A4 substrates may result in lower exposure to these remedies.
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modafinil will improve the level or result of citalopram by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Check. Citalopram twenty mg/working day is the maximum advisable dose for patients using CYP2C19 inhibitors as a result of possibility of QT prolongation.
Consequently, coadministration of ozanimod with medicine that may raise norepinephrine or serotonin isn't encouraged. Keep track of for hypertension with concomitant use.
modafinil will enhance the degree or effect of flibanserin by impacting hepatic enzyme CYP2C19 metabolism.
fosphenytoin will reduce the extent or result of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.